Article
[KRAS gene mutation in colorectal cancer].
Revista medica de Chile - 1 Sept 2013
Roa Iván, Sánchez Tamara, Majlis Alejandro, Schalper Kurt
Abstract excerpt
BACKGROUND: KRAS oncogene is involved in colorectal carcinogenesis in 22 to 45% of cases. AIM: To determine the frequency, types and distribution of KRAS mutations in colorectal cancer. MATERIAL AND METHODS: KRAS mutations studies were carried out in primary tumors and metastases of colo-rectal cancer from 56 women aged 60 ± 14 years and 53 men aged 61 ± 11 years. Formalin fixed and paraffin embedded tissue...
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