Article
Lack of KRAS gene mutations in chronic myeloid leukemia in Iran.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Kooshyar Mohammad Mahdi, Ayatollahi Hossein, Keramati Mohammad Reza, Sadeghian Mohammad Hadi, Miri Mohsen, Sheikhi Maryam
Abstract excerpt
BACKGROUND: The single most common proto-oncogene change in human neoplasms is a point mutation in RAS genes. A wide range of variation in frequency of KRAS mutations has been seen in hematologic malignancies. Despite this, RAS roles in leukemogenesis remain unclear. The frequency of KRAS mutatio...
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