Article
KRAS gene mutations in correlation with clinicopathological features of colorectal carcinomas in Indian patient cohort.
Medical oncology (Northwood, London, England) - 1 Jan 2013
Patil Harshali, Korde Rajesh, Kapat Arnab
Abstract excerpt
KRAS gene mutations have been identified as a predictive molecular marker to predict the sensitivity of tumors to anti-EGFR therapeutics. The variability of clinical response to anti-EGFR agents has highlighted the need to select the appropriate patients who can benefit from the treatment. We examined the prevalence of KRAS mutations in 1,323 colorectal cancer patients from different regions of India and its...
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