Article
DTF1 is a core component of RNA-directed DNA methylation and may assist in the recruitment of Pol IV.
Proceedings of the National Academy of Sciences of the United States of America - 14 May 2013
Zhang Heng, Ma Ze-Yang, Zeng Liang, Tanaka Kaori, Zhang Cui-Jun, Ma Jun, Bai Ge, Wang Pengcheng, Zhang Su-Wei, Liu Zhang-Wei, Cai Tao, Tang Kai, Liu Renyi, Shi Xiaobing, He Xin-Jian, Zhu Jian-Kang
Abstract excerpt
DNA methylation is an important epigenetic mark in many eukaryotic organisms. De novo DNA methylation in plants can be achieved by the RNA-directed DNA methylation (RdDM) pathway, where the plant-specific DNA-dependent RNA polymerase IV (Pol IV) transcribes target sequences to initiate 24-nt siRNA production and action. The putative DNA binding protein DTF1/SHH1 of Arabidopsis has been shown to associate with Pol...
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