Article
The PRP6-like splicing factor STA1 is involved in RNA-directed DNA methylation by facilitating the production of Pol V-dependent scaffold RNAs.
Nucleic acids research - 1 Oct 2013
Dou Kun, Huang Chao-Feng, Ma Ze-Yang, Zhang Cui-Jun, Zhou Jin-Xing, Huang Huan-Wei, Cai Tao, Tang Kai, Zhu Jian-Kang, He Xin-Jian
Abstract excerpt
DNA methylation is a conserved epigenetic marker in plants and animals. In Arabidopsis, DNA methylation can be established through an RNA-directed DNA methylation (RdDM) pathway. By screening for suppressors of ros1, we identified STA1, a PRP6-like splicing factor, as a new RdDM regulator. Whole-genome bisulfite sequencing suggested that STA1 and the RdDM pathway share a large number of common targets in the...
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