Article
RNA-directed DNA methylation and plant development require an IWR1-type transcription factor.
EMBO reports - 1 Jan 2010
Kanno Tatsuo, Bucher Etienne, Daxinger Lucia, Huettel Bruno, Kreil David P, Breinig Frank, Lind Marc, Schmitt Manfred J, Simon Stacey A, Gurazada Sai Guna Ranjan, Meyers Blake C, Lorkovic Zdravko J, Matzke Antonius J M, Matzke Marjori
Abstract excerpt
RNA-directed DNA methylation (RdDM) in plants requires two RNA polymerase (Pol) II-related RNA polymerases, namely Pol IV and Pol V. A genetic screen designed to reveal factors that are important for RdDM in a developmental context in Arabidopsis identified DEFECTIVE IN MERISTEM SILENCING 4 (DMS4). Unlike other mutants defective in RdDM, dms4 mutants have a pleiotropic developmental phenotype. The DMS4 protein is...
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