Article
A Pre-mRNA-splicing factor is required for RNA-directed DNA methylation in Arabidopsis.
PLoS genetics - 1 Jan 2013
Huang Chao-Feng, Miki Daisuke, Tang Kai, Zhou Hao-Ran, Zheng Zhimin, Chen Wei, Ma Ze-Yang, Yang Lan, Zhang Heng, Liu Renyi, He Xin-Jian, Zhu Jian-Kang
Abstract excerpt
Cytosine DNA methylation is a stable epigenetic mark that is frequently associated with the silencing of genes and transposable elements (TEs). In Arabidopsis, the establishment of DNA methylation is through the RNA-directed DNA methylation (RdDM) pathway. Here, we report the identification and characterization of RDM16, a new factor in the RdDM pathway. Mutation of RDM16 reduced the DNA methylation levels and...
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