Article
Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci.
Human mutation - 1 Sept 2005
Kim Unkyung, Wooding Stephen, Ricci Dante, Jorde Lynn B, Drayna Dennis
Abstract excerpt
Bitter taste perception in humans is mediated by receptors encoded by 25 genes that together comprise the TAS2R (or T2R) gene family. The ability to identify the ligand(s) for each of these receptors is dependent on understanding allelic variation in TAS2R genes, which may have a significant effect on ligand recognition. To investigate the extent of coding variation among TAS2R alleles, we performed a...
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