Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci.

doi:10.1002/humu.20203

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Article

Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci.

Human mutation - 1 Sept 2005

Kim Unkyung, Wooding Stephen, Ricci Dante, Jorde Lynn B, Drayna Dennis

Abstract excerpt

Bitter taste perception in humans is mediated by receptors encoded by 25 genes that together comprise the TAS2R (or T2R) gene family. The ability to identify the ligand(s) for each of these receptors is dependent on understanding allelic variation in TAS2R genes, which may have a significant effe...

Topics

Alleles
Genetic Variation
Haplotypes
Humans
Ligands
Polymorphism, Single Nucleotide
Receptors, Cell Surface
Receptors, G-Protein-Coupled
Selection, Genetic
Sequence Analysis, DNA
Taste
Taste Buds
Taste Receptors, Type 2

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