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Article

The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Jan 2013

Born Stephan, Levit Anat, Niv Masha Y, Meyerhof Wolfgang, Behrens Maik

Abstract excerpt

Bitter taste is a basic taste modality, required to safeguard animals against consuming toxic substances. Bitter compounds are recognized by G-protein-coupled bitter taste receptors (TAS2Rs). The human TAS2R10 responds to the toxic strychnine and numerous other compounds. The mechanism underlying the development of the broad tuning of some TAS2Rs is not understood. Using comparative modeling, site-directed...

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Identifiers

PMID: 23283334
DOI: 10.1523/JNEUROSCI.3248-12.2013
PMCID: PMC6618634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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