Article
[A study of parent-of-origin effect of single nucleotide polymorphisms of imprinted gene KCNQ1 on risk for hypertension].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 10 Jul 2026
Ye X Y, Zhang H Y, Guo H D, Peng H X, Hou T J, Li Y X, Tan Y X, Gong H Y, Wu W F, Zhao Y, Wang M Y, Wu Y Q, Qin X Y, Li J, Chen D F, Hu Y H, Wu T
Abstract excerpt
Objective: To understand the potential parent-of-origin effect (POE) of imprinted gene KCNQ1 on the risk for hypertension by using a family-based design. Methods: Probands and their relatives in 9 rural areas in Fangshan District, Beijing, were included in this study. Mixed-effects model was used to evaluate the association between single nucleotide polymorphisms (SNPs) in the KCNQ1 gene and hypertension. The POE...
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