Article
Genetics of Type 2 Diabetes: It Matters From Which Parent We Inherit the Risk.
The review of diabetic studies : RDS - 1 Jan 2000
Lyssenko Valeriya, Groop Leif, Prasad Rashmi B
Abstract excerpt
Type 2 diabetes (T2D) results from a co-occurrence of genes and environmental factors. There are more than 120 genetic loci suggested to be associated with T2D, or with glucose and insulin levels in European and multi-ethnic populations. Risk of T2D is higher in the offspring if the mother rather than the father has T2D. Genetically, this can be associated with a unique parent-of-origin (PoO) transmission of risk...
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