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Article

[Pharmacogenetics and antiepileptic drug metabolism: implication of genetic variants in cytochromes P450].

Revista de neurologia - 1 May 2013

Saldaña-Cruz Ana Miriam, Sánchez-Corona José, Márquez de Santiago Daniel Alejandro, García-Zapién Alejandra Guadalupe, Flores-Martínez Silvia Esperanza

Abstract excerpt

INTRODUCTION: Antiepileptic drugs (AEDs) are used for the seizures control in patients with epilepsy, however 20-30% of epileptic patients are drug resistant. Several factors contributing to the variability of the AEDs response, and this variability can be partially attributed to the presence of sequence variations (polymorphisms) in genes encoding enzymes involved in the AEDs metabolism. AIM: To describe the...

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PMID: 23629749

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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