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Article

Implications of pharmacogenetics for the therapeutic use of antiepileptic drugs.

Expert opinion on drug metabolism & toxicology - 1 Mar 2014

Piana Chiara, Antunes Natalicia de Jesus, Della Pasqua Oscar

Abstract excerpt

INTRODUCTION: Epilepsy is a chronic neurological disease manifesting as recurrent seizures. Despite the availability of numerous antiepileptic drugs (AEDs), one-third of the patients are not responsive to treatment. Such inter-individual variability in the response to AEDs may be partly explained by genetic differences. This review summarizes the pharmacogenetics (PGx) of AEDs. In addition, a model-based approach...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24460510
DOI: 10.1517/17425255.2014.872630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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