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Article

Synthetic sickness or lethality points at candidate combination therapy targets in glioblastoma

30 Apr 2013

Abstract excerpt

Synthetic lethal interactions in cancer hold the potential for successful combined therapies, which would avoid the difficulties of single molecule-targeted treatment. Identification of interactions that are specific for human tumors is an open problem in cancer research. This work aims at deciphering synthetic sick or lethal interactions directly from somatic alteration, expression and survival data of cancer...

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Share to Advanced biosensing and bioanalysis techniques
Share to Cancer Genomics and Diagnostics
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23629686
DOI: 10.1002/ijc.28235

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