Article

mslp: a comprehensive pipeline in predicting cancer mutations specific synthetic lethal partners

2021-12-16

Abstract excerpt

<h4>Background</h4> Mutation specific synthetic lethal partners (SLPs) offer significant insights in identifying novel targets and designing personalized treatments in cancer studies. Large scale genetic screens in cell lines and model organisms provide crucial resources for mining SLPs, yet those experiments are expensive and might be difficult to set up. Various computational methods have been proposed to predi...

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Literature Corpus work: a4361fe7-db12-5615-9ed7-ca1184333dfa
DOI: 10.1101/2021.12.15.472776

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