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An integrated and sensitive detection platform for biosensing application based on Fe@Au magnetic nanoparticles as bead array carries.

Biosensors & bioelectronics - 15 Dec 2010

Liu Hongna, Li Song, Liu Lishang, Tian Lan, He Nongyue

Abstract excerpt

A sensitive and selective biosensor platform suited for SNP type using Fe@Au magnetic nanoparticles (GMNPs) to fabricate bead array is described. This new platform integrates the rapid binding kinetics of magnetic nanoparticles carriers, the multiplexing and encoding capabilities of chips, and tagged array. As a DNA sensor, the biotinylated single-stranded DNA was obtained by asymmetry PCR amplification, and then...

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PMID: 20728338
DOI: 10.1016/j.bios.2010.07.078

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