Article
Association between p53 gene variants and oral cancer susceptibility in population from Gujarat, West India.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Patel Kinjal R, Vajaria Bhairavi N, Begum Rasheedunnisa, Shah Franky D, Patel Jayendra B, Shukla Shilin N, Patel Prabhudas S
Abstract excerpt
BACKGROUND: p53 gene variants i.e. 16 bp duplication in intron 3, Arg72Pro in exon 4 and G>A in intron 6 have been reported to modulate susceptibility to various malignancies. Therefore, the present study evaluated the role of these p53 polymorphisms in oral cancer susceptibility in a population from Gujarat, West India. METHOD: Genotype frequencies at the three p53 loci in 110 controls and 79 oral cancer cases...
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