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Article

TP53 Pro72 allele is enriched in oral tongue cancer and frequently mutated in esophageal cancer in India.

PloS one - 1 Jan 2014

Adduri Raju S R, Katamoni Rajender, Pandilla Ramaswamy, Madana Sandeep N, Paripati Arun Kumar, Kotapalli Viswakalyan, Bashyam Murali Dharan

Abstract excerpt

PURPOSE: The tumor suppressor p53 is known to be inactivated frequently in various cancers. In addition, germline polymorphisms in TP53 are known to affect protein function and influence risk of developing different types of cancers. In this study, we analyzed the association of TP53 Pro72Arg polymorphism with squamous cell carcinoma of oral tongue (SCCOT) and esophagus (ESCC) in India. METHODS: We assessed the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25436609
DOI: 10.1371/journal.pone.0114002
PMCID: PMC4250174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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