Article
P53 (Pro72Arg) polymorphism associated with the risk of oral squamous cell carcinoma in gutka, niswar and manpuri addicted patients of Pakistan.
Oral oncology - 1 Aug 2013
Saleem Saima, Azhar Abid, Hameed Abdul, Khan Mansoor Ahmed, Abbasi Zubair Ahmed, Qureshi Navid Rashid, Ajmal Muhammad
Abstract excerpt
OBJECTIVES: The chewing habit of paan, chhaliya, and tobacco is common in the traditional culture of Pakistan. Currently, niswar, gutka and manpuri are also commercially available in the Pakistani market. Epidemiologic evidences and increased rate of oral squamous cell carcinoma (OSCC) cases may indicate a direct relationship of these chewing habits with oral carcinogenesis. The p53 gene has been known to be a...
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