Article
Determination of p53 genotypes in oral cancer patients from India.
British journal of cancer - 23 Mar 2001
Tandle A T, Sanghvi V, Saranath D
Abstract excerpt
The p53 tumour suppressor gene is inactivated in various types of human cancers, and has been implicated as an early event in several cancers. A p53 Pro/Arg polymorphism at exon 4 codon 72, has been suggested to be involved in susceptibility to cancers as well. Hence, in the current study, we investigated p53 exon 4 codon 72 polymorphism using Proline or Arginine specific primers from the peripheral blood cells...
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