Article
P53 gene codon 72 polymorphism in patients with oral squamous cell carcinoma in the population of northern Iran.
Medicina oral, patologia oral y cirugia bucal - 1 Nov 2014
Sina Mahmud, Pedram Mehrdad, Ghojazadeh Morteza, Kochaki Ahmad, Aghbali Amirala
Abstract excerpt
OBJECTIVES: Squamous cell carcinoma is the most common cancer of the oral cavity, and several etiologic factors are involved in its developing. Single nucleotide polymorphism (SNP) of the P53 gene codon 72 (P53c72) changes the structure of the protein and affects its activity. The prevalence of P53c72 different genotypes, which seems to vary with race and geographic location, has shown a strong correlation with...
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