Article
Role of p53 and p73 genes polymorphisms in susceptibility to esophageal cancer: a case control study in a northern Indian population.
Molecular biology reports - 1 Feb 2012
Umar Meenakshi, Upadhyay Rohit, Khurana Rohini, Kumar Shaleen, Ghoshal Uday Chand, Mittal Balraj
Abstract excerpt
Genetic variants in p53 and in its homologue p73 may modulate Esophageal Cancer (EC) risk because they are supposed to influence cell cycle progression, apoptosis and DNA repair. Therefore, we aimed to evaluate the association of p53 intron3 16 bp duplication and p73 G4C14-to-A4T14 polymorphisms...
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