Article
Cloning of Xenopus RCC1 cDNA, a homolog of the human RCC1 gene: complementation of tsBN2 mutation and identification of the product.
Journal of biochemistry - 1 Feb 1990
Nishitani H, Kobayashi H, Ohtsubo M, Nishimoto T
Abstract excerpt
We isolated a cDNA clone from Xenopus cDNA libraries for the homolog of the human RCC1 gene, which is considered to be a regulator for the onset of chromosome condensation. The cloned Xenopus RCC1 cDNA encoded a protein of 424 amino acids which had the same seven homologous repeated domains of ab...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Cycle Proteins
- Cell Line
- Cloning, Molecular
- DNA
- DNA-Binding Proteins
- Gene Expression
- Genes
- Genetic Complementation Test
- Guanine Nucleotide Exchange Factors
- Humans
- Immunoblotting
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Oocytes