Article
Fusion of the transcription factor <i>TFE3</i> gene to a novel gene, <i>PRCC</i> , in t(X;1)(p11;q21)-positive papillary renal cell carcinomas
24 Dec 1996
Abstract excerpt
The (X;1)(p11;q21) translocation is a recurrent chromosomal abnormality in a subset of human papillary renal cell carcinomas, and is sometimes the sole cytogenetic abnormality present. Via positional cloning, we were able to identify the genes involved. The translocation results in a fusion of the transcription factor TFE3 gene on the X chromosome to a novel gene, designated PRCC, on chromosome 1. Through this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.