Article
The yeast SRM1 protein and human RCC1 protein share analogous functions.
Cell regulation - 1 Oct 1991
Clark K L, Ohtsubo M, Nishimoto T, Goebl M, Sprague G F
Abstract excerpt
The Saccharomyces cerevisiae protein SRM1 and the mammalian protein RCC1 have amino acid sequence similarity throughout their lengths. SRM1 was defined by a recessive mutation in yeast that both activates the signal transduction pathway required for mating and leads to arrest in the G1 phase of the cell cycle. RCC1 was defined by a recessive mutation in hamster cells that causes premature chromosome condensation...
Topics
- Amino Acid Sequence
- Cell Cycle
- Cell Cycle Proteins
- Chromosomes
- DNA-Binding Proteins
- Fungal Proteins
- Genetic Complementation Test
- Guanine Nucleotide Exchange Factors
- Humans
- Molecular Sequence Data
- Mutation