Article
Mutation of the hamster cell cycle gene RCC1 is complemented by the homologous genes of Drosophila and S.cerevisiae.
The EMBO journal - 1 May 1991
Ohtsubo M, Yoshida T, Seino H, Nishitani H, Clark K L, Sprague G F, Frasch M, Nishimoto T
Abstract excerpt
The RCC1 gene has been isolated from several vertebrates, including human, hamster and Xenopus. Genes similar to RCC1, namely BJ1 and SRM1/PRP20, have been isolated from the insect Drosophila and from the budding yeast Saccharomyces cerevisiae. A mutation of the RCC1 gene in the hamster BHK21 cell line, tsBN2, confers pleiotropic phenotypes, including G1 arrest and premature induction of mitosis in cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.