The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homolog of the vertebrate gene Regulator of Chromatin Condensation, RCC1.

doi:10.1002/j.1460-2075.1991.tb08064.x

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Article

The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homolog of the vertebrate gene Regulator of Chromatin Condensation, RCC1.

The EMBO journal - 1 May 1991

Frasch M

Abstract excerpt

Using monoclonal antibodies I have identified a nuclear protein of Drosophila, BJ1 (Mr approximately 68 kd), and isolated its gene. Biochemical analysis demonstrates that the BJ1 protein is associated with nucleosomes and is released from chromatin by agents which intercalate into DNA, as previously shown for the high mobility group proteins (HMGs). On polytene chromosomes the protein is localized in all bands,...

Topics

Amino Acid Sequence
Animals
Antibodies, Monoclonal
Antigens
Base Sequence
Blastoderm
Cell Nucleus
Chromatin
Chromosomes
DNA
DNA-Binding Proteins
Drosophila

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Drosophila Proteins

Fluorescent Antibody Technique

Gene Expression Regulation

Guanine Nucleotide Exchange Factors

Insect Hormones

Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 2022188
DOI: 10.1002/j.1460-2075.1991.tb08064.x
PMCID: PMC452777

Genes

RCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2022188-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homolog of the vertebrate gene Regulator of Chromatin Condensation, RCC1.PMID 2022188Read ↗

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