Article
RCC1 and nuclear organization.
Molecular biology of the cell - 1 Jun 1997
Huang S, Mayeda A, Krainer A R, Spector D L
Abstract excerpt
We have examined the effect of RCC1 function on the nuclear organization of pre-mRNA splicing factors and poly(A)+ RNA in the tsBN2 cells, a RCC1 temperature-sensitive mutant cell line. We have found that at 4-6 h after shifting cells from the permissive temperature (32.5 degrees C) to the restri...
Topics
- Animals
- Cell Compartmentation
- Cell Cycle Proteins
- Cell Line
- Cell Nucleus
- Cricetinae
- DNA-Binding Proteins
- Guanine Nucleotide Exchange Factors
- Mutation
- Nuclear Proteins
- RNA Splicing
- RNA, Messenger
- Ribonucleoproteins, Small Nuclear
- Temperature
- Transcription, Genetic