Article
RCC1 and nuclear organization.
Molecular biology of the cell - 1 Jun 1997
Huang S, Mayeda A, Krainer A R, Spector D L
Abstract excerpt
We have examined the effect of RCC1 function on the nuclear organization of pre-mRNA splicing factors and poly(A)+ RNA in the tsBN2 cells, a RCC1 temperature-sensitive mutant cell line. We have found that at 4-6 h after shifting cells from the permissive temperature (32.5 degrees C) to the restrictive temperature (39.5 degrees C), both small nuclear ribonucleoprotein particles and a general splicing factor SC35...
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