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Article

DNA binding specificities of the long zinc-finger recombination protein PRDM9.

Genome biology - 24 Apr 2013

Billings Timothy, Parvanov Emil D, Baker Christopher L, Walker Michael, Paigen Kenneth, Petkov Petko M

Abstract excerpt

BACKGROUND: Meiotic recombination ensures proper segregation of homologous chromosomes and creates genetic variation. In many organisms, recombination occurs at limited sites, termed 'hotspots', whose positions in mammals are determined by PR domain member 9 (PRDM9), a long-array zinc-finger and chromatin-modifier protein. Determining the rules governing the DNA binding of PRDM9 is a major issue in understanding...

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Identifiers

PMID: 23618393
DOI: 10.1186/gb-2013-14-4-r35
PMCID: PMC4053984

Genes

PRDM9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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