Article
Natural killer KIR3DS1 is closely associated with HCV viral clearance and sustained virological response in HIV/HCV patients.
PloS one - 1 Jan 2013
Rivero-Juarez Antonio, Gonzalez Rafael, Camacho Angela, Manzanares-Martin Barbara, Caruz Antonio, Martinez-Peinado Antonio, Torre-Cisneros Julian, Pineda Juan A, Peña José, Rivero Antonio
Abstract excerpt
AIM: To evaluate the influence of the presence of the killer cell immunoglobulin-like receptor (KIR) 3DS1 on HCV treatment response in HIV/HCV genotype 1 co-infected patients. METHODS: HIV/HCV co-infected patients were included. KIR3DS1, their specific HLA-B ligands and IL28B gene were genotyped. Reductions of plasma HCV RNA levels between baseline and week 1, week 2 and week 4 were analyzed for IL28B genotype...
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