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Article

Characterization of Prdm9 in equids and sterility in mules.

PloS one - 1 Jan 2013

Steiner Cynthia C, Ryder Oliver A

Abstract excerpt

Prdm9 (Meisetz) is the first speciation gene discovered in vertebrates conferring reproductive isolation. This locus encodes a meiosis-specific histone H3 methyltransferase that specifies meiotic recombination hotspots during gametogenesis. Allelic differences in Prdm9, characterized for a variable number of zinc finger (ZF) domains, have been associated with hybrid sterility in male house mice via spermatogenic...

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Share to Amino Acid Sequence
Share to Equidae
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone-Lysine N-Methyltransferase

Share to Hybridization, Genetic

Share to Infertility

Share to Protein Structure, Tertiary

Share to Selection, Genetic

Source

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Identifiers

PMID: 23613924
DOI: 10.1371/journal.pone.0061746
PMCID: PMC3632555

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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