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Article

The functional MICA-129 polymorphism is associated with skin but not joint manifestations of psoriatic disease independently of HLA-B and HLA-C.

Tissue antigens - 1 Jul 2013

Pollock R A, Chandran V, Pellett F J, Thavaneswaran A, Eder L, Barrett J, Rahman P, Farewell V, Gladman D D

Abstract excerpt

A methionine/valine polymorphism at amino acid 129 of the major histocompatibility complex class I chain-related gene A (MICA-129) categorizes alleles into strong and weak binders of the natural killer (NK) and T-cell receptor NKG2D. We investigated whether MICA-129 is differentially associated with skin and joint manifestations of psoriatic disease (PsD) independently of human leukocyte antigen (HLA)-C and HLA-B...

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Source

Identifiers

PMID: 23611695
DOI: 10.1111/tan.12126

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The functional MICA-129 polymorphism is associated with skin but not joint manifestations of psoriatic disease independently of HLA-B and HLA-C.PMID 23611695Read ↗

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Differential major histocompatibility complex class I chain-related A allele associations with skin and joint manifestations of psoriatic disease.Semantic proximity Read ↗

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