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Article

Normal dynactin complex function during synapse growth in Drosophila requires membrane binding by Arfaptin.

Molecular biology of the cell - 1 Jun 2013

Chang Leo, Kreko Tabita, Davison Holly, Cusmano Tim, Wu Yimin, Rothenfluh Adrian, Eaton Benjamin A

Abstract excerpt

Mutations in DCTN1, a component of the dynactin complex, are linked to neurodegenerative diseases characterized by a broad collection of neuropathologies. Because of the pleiotropic nature of dynactin complex function within the neuron, defining the causes of neuropathology in DCTN1 mutants has been difficult. We combined a genetic screen with cellular assays of dynactin complex function to identify genes that...

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Identifiers

PMID: 23596322
DOI: 10.1091/mbc.E12-09-0697
PMCID: PMC3667727

Genes

DCTN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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