Article
Protease genotypes in patients failing protease inhibitor-based antiretroviral therapy at a pediatric center in Botswana.
The Pediatric infectious disease journal - 1 Oct 2013
Gomila Andres, Kirk Brianna, Marape Marape, Anabwani Gabriel, Tolle Michael
Abstract excerpt
With increasing use of protease inhibitors (PI) in Botswana, a large proportion of HIV-infected children are now exposed to PI-based regimens. There is limited protease genotype data from African children and adolescents who have failed PI-based antiretroviral therapy. We describe a cohort of pediatric HIV-infected patients experiencing virologic failure at time of second-line or salvage PI-based regimens and...
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