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Article

Impact of human immunodeficiency virus type 1 subtype C on drug resistance mutations in patients from Botswana failing a nelfinavir-containing regimen.

Antimicrobial agents and chemotherapy - 1 Jun 2006

Doualla-Bell Florence, Avalos Ava, Gaolathe Tendani, Mine Madisa, Gaseitsiwe Simani, Ndwapi Ndwapi, Novitsky Vladimir A, Brenner Bluma, Oliveira Maureen, Moisi Daniella, Moffat Howard, Thior Ibou, Essex Max, Wainberg Mark A

Abstract excerpt

Among 16 human immunodeficiency virus-infected (subtype C) Batswana patients who failed nelfinavir (NFV)-containing regimens, the most prevalent mutation observed was D30N (54%), followed by L90M (31%). L89I, K20T/I, and E35D polymorphic changes were also identified. These findings suggest that s...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16723586
DOI: 10.1128/AAC.01447-05
PMCID: PMC1479146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16723586-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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