Genotype-guided antiretroviral regimens in children with multidrug-resistant HIV-1 infection.

doi:10.1038/pr.2016.53

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Article

Genotype-guided antiretroviral regimens in children with multidrug-resistant HIV-1 infection.

Pediatric research - 1 Jul 2016

Huerta-García Gloria, Vazquez-Rosales José G, Mata-Marín José A, Peregrino-Bejarano Leoncio, Flores-Ruiz Eric, Solórzano-Santos Fortino

Abstract excerpt

BACKGROUND: Genotyping tests were developed to attenuate the impact of viral resistance. Information about the efficacy in genotype base antiretroviral therapy in children is rare and even more in low- and middle-income countries. METHODS: Sixteen children with antiretroviral therapy (ART) failure and triple-class drug-resistant viruses were included in this study. Protease and retrotranscriptase genotypes were...

Topics

Adolescent
Anti-Retroviral Agents
CD4 Lymphocyte Count
Child
Darunavir
Drug Resistance, Multiple, Viral
Female
Genotype
HIV Infections
HIV-1
Humans
Male
Nitriles
Poverty
Pyridazines

Source

Open in PubMed

Identifiers

PMID: 26999770
DOI: 10.1038/pr.2016.53

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Pyrimidines

RNA, Viral

Raltegravir Potassium