Article
Second-line HIV Treatment in Ugandan Children: Favorable Outcomes and No Protease Inhibitor Resistance.
Journal of tropical pediatrics - 1 Apr 2017
Boerma Ragna S, Kityo Cissy, Boender T Sonia, Kaudha Elizabeth, Kayiwa Joshua, Musiime Victor, Mukuye Andrew, Kiconco Mary, Nankya Immaculate, Nakatudde Lilian, Mugyenyi Peter N, Boele van Hensbroek Michael, Rinke de Wit Tobias F, Sigaloff Kim C E, Calis Job C J
Abstract excerpt
Background: Data on pediatric second-line antiretroviral treatment (ART) outcomes are scarce, but essential to evaluate second-line and design third-line regimens. Methods: Children ≤12 years switching to second-line ART containing a protease inhibitor (PI) in Uganda were followed for 24 months. Viral load (VL) was determined at switch to second-line and every 6 months thereafter; genotypic resistance testing was...
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