Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional stalling in B-lymphocytes

1 May 2013

Abstract excerpt

B cells utilize three DNA alteration strategies-V(D)J recombination, somatic hypermutation (SHM) and class switch recombination (CSR)-to somatically mutate their genome, thereby expressing a plethora of antibodies tailor-made against the innumerable antigens they encounter while in circulation. Of these three events, the single-strand DNA cytidine deaminase, Activation Induced cytidine Deaminase (AID), is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to DNA Repair Mechanisms
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23584095
DOI: 10.4161/trns.24556

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional stalling in B-lymphocytesPMID 23584095Read ↗

AID in Antibody Diversification: There and Back Again.Semantic proximity Read ↗

Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscapeSemantic proximity Read ↗

DNA Lesions and Repair in Immunoglobulin Class Switch Recombination and Somatic HypermutationSemantic proximity Read ↗

DNA deamination in immunitySemantic proximity Read ↗

AID-initiated purposeful mutations in immunoglobulin genes.Semantic proximity Read ↗

Epigenomic Modifications Mediating Antibody MaturationSemantic proximity Read ↗

Mismatch-mediated error prone repair at the immunoglobulin genes.Semantic proximity Read ↗

AID Biology: A pathological and clinical perspectiveSemantic proximity Read ↗

Generating and repairing genetically programmed DNA breaks during immunoglobulin class switch recombinationSemantic proximity Read ↗

Transcription-targeted DNA deamination by the AID antibody diversification enzymeSemantic proximity Read ↗

The Role of DNA Repair in Immunological Diversity: From Molecular Mechanisms to Clinical RamificationsSemantic proximity Read ↗

Base Excision Repair in the Immune System: Small DNA Lesions With Big ConsequencesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.