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Article

AID-initiated purposeful mutations in immunoglobulin genes.

Advances in immunology - 1 Jan 2007

Goodman Myron F, Scharff Matthew D, Romesberg Floyd E

Abstract excerpt

Exposure brings risk to all living organisms. Using a remarkably effective strategy, higher vertebrates mitigate risk by mounting a complex and sophisticated immune response to counter the potentially toxic invasion by a virtually limitless army of chemical and biological antagonists. Mutations are almost always deleterious, but in the case of antibody diversification there are mutations occurring at hugely...

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Share to AICDA (Activation-Induced Cytidine Deaminase)
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PMID: 17560274
DOI: 10.1016/S0065-2776(06)94005-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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