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Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease

11 Apr 2013

Abstract excerpt

INTRODUCTION: Progressive neuronal loss is a key feature in Alzheimer's disease (AD), which is the most common neurodegenerative disorder in the aging population. Currently, there are no therapeutic means to intervene neuronal damage in AD and therefore innovative approaches to discover novel strategies for the treatment of AD are needed. Based on the prevailing amyloid cascade hypothesis, it is conceivable that...

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PMID: 23573918
DOI: 10.1517/14728222.2013.789862

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