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Article

Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies

6 Apr 2017

Abstract excerpt

Among the LDL receptor (LDLR) family members, the roles of LDLR-related protein (LRP)1 in the pathogenesis of Alzheimer's disease (AD), especially late-onset AD, have been the most studied by genetic, neuropathological, and biomarker analyses (clinical studies) or cellular and animal model systems (preclinical studies) over the last 25 years. Although there are some conflicting reports, accumulating evidence from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28381441
DOI: 10.1194/jlr.r075796

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