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Article

Prefrontal cognitive systems in schizophrenia: towards human genetic brain mechanisms.

Cognitive neuropsychiatry - 1 Jan 2009

Tan Hao-Yang, Callicott Joseph H, Weinberger Daniel R

Abstract excerpt

Schizophrenia has complex genetic heritability. It is also genetically heterogeneous. To the extent that genes are associated with symptom constellations in schizophrenia, they do so by affecting the development and function of neural systems that mediate the expression of such diverse behavioral, cognitive and perceptual phenomena. The genetic mechanisms of human brain dysfunction remain to be well understood....

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Identifiers

PMID: 19634031
DOI: 10.1080/13546800903091665

Genes

AKT1
COMT

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