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Article

Generation and characterization of virus-free reprogrammed melanoma cells by the piggyBac transposon.

Journal of cancer research and clinical oncology - 1 Sept 2013

Yin Juan, Fan Yongna, Qin Dingxin, Xiaocui Bian Xiaocui, Bi Xiaobao

Abstract excerpt

PURPOSE: Reprogramming of cancer cells to stem cell-like state provides a promising tool for the study of cancer pathogenesis and drug screening. However, most instances of direct reprogramming have been achieved by forced co-expression of defined transcription factors using viral vectors. Retroviral transduction as well as the ectopic expression of reprogramming factors may alter the differentiation potential of...

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Identifiers

PMID: 23571855
DOI: 10.1007/s00432-013-1431-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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