Article
De- and re-differentiation of the melanocytic lineage.
European journal of cell biology - 1 Jan 2000
Larribere Lionel, Utikal Jochen
Abstract excerpt
Terminally differentiated cells can be reprogrammed by the transient, ectopic overexpression of different sets of genes into induced pluripotent stem cells (iPSCs). This process not only has considerable implications for regenerative medicine but is also highly relevant to multiple stages of oncogenesis, including melanoma. In other settings, the de-differentiation of normal and tumor cells is also responsible...
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