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Article

Embryonic stem‐cell‐preconditioned microenvironment induces loss of cancer cell properties in human melanoma cells

26 Jul 2011

Abstract excerpt

The cancer microenvironment affects cancer cell proliferation and growth. Embryonic stem (ES)-preconditioned 3-dimensional (3-D) culture of cancer cells induces cancer cell reprogramming and results in a change in cancer cell properties such as differentiation and migration in skin melanoma. However, the mechanism has not yet been clarified. Using the ES-preconditioned 3-D microenvironment model, we provide...

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PMID: 21787378
DOI: 10.1111/j.1755-148x.2011.00891.x

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