Article
Fusion between tumor cells enhances melanoma metastatic potential.
Journal of cancer research and clinical oncology - 1 Oct 2012
Mi Ruifang, Pan Chunxiao, Bian Xiaocui, Song Liqiang, Tian Wenjia, Cao Fang, Yin Juan, Peng Haiyong, Ma Jianhui
Abstract excerpt
PURPOSE: Malignant melanoma, characterized by early distant metastasis to the lungs and brain, is a leading cause of mortality related to skin cancer. Cell fusion and the subsequent aneuploidy, commonly observed in melanoma, are associated with poor prognosis. However, the pathological consequenc...
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