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Article

Ku80-deleted cells are defective at base excision repair.

Mutation research - 1 Jan 2000

Li Han, Marple Teresa, Hasty Paul

Abstract excerpt

Ku80 forms a heterodimer with Ku70, called Ku, that repairs DNA double-strand breaks (DSBs) via the nonhomologous end joining (NHEJ) pathway. As a consequence of deleting NHEJ, Ku80-mutant cells are hypersensitive to agents that cause DNA DSBs like ionizing radiation. Here we show that Ku80 delet...

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Identifiers

PMID: 23567907
DOI: 10.1016/j.mrfmmm.2013.03.010
PMCID: PMC3721509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23567907-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Ku80-deleted cells are defective at base excision repair.PMID 23567907Read ↗

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