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Article

Molecular and biochemical characterization of new X-ray-sensitive hamster cell mutants defective in Ku80.

Nucleic acids research - 1 Oct 1998

Errami A, Finnie N J, Morolli B, Jackson S P, Lohman P H, Zdzienicka M Z

Abstract excerpt

Ku, a heterodimer of approximately 70 and approximately 80 kDa subunits, is a nuclear protein that binds to double-stranded DNA ends and is a component of the DNA-dependent protein kinase (DNA-PK). Cell lines defective in Ku80 belong to group XRCC5 of ionizing radiation-sensitive mutants. Five new independent Chinese hamster cell mutants, XR-V10B, XR-V11B, XR-V12B, XR-V13B and XR-V16B, that belong to this group...

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Identifiers

PMID: 9742232
DOI: 10.1093/nar/26.19.4332
PMCID: PMC147872

Genes

XRCC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular and biochemical characterization of new X-ray-sensitive hamster cell mutants defective in Ku80.PMID 9742232Read ↗

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