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Article

CYP2D6*2 Polymorphism as a Predictor of Failed Outpatient Tramadol Therapy in Postherpetic Neuralgia Patients.

American journal of therapeutics - 1 Jan 2000

Nasare Namita Vilas, Banerjee Basu Dev, Suryakantrao Deshmukh Pravin, Mediratta Pramod Kumari, Saxena Ashok Kumar, Ahmed Rafat Sultana, Bhattacharya Sambit Nath

Abstract excerpt

Human cytochrome P4502D6 (CYP2D6) gene is highly polymorphic, leading to wide interindividual ethnic differences in CYP2D6-mediated drug metabolism. Its activity ranges from complete deficiency to excessive activity, potentially causing toxicity of the medication or therapeutic failure with recom...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23567787
DOI: 10.1097/MJT.0b013e31826fc491

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23567787-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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