Article
Genetic variation in GAD1 is associated with cortical thickness in the parahippocampal gyrus.
Journal of psychiatric research - 1 Jul 2013
Brauns Stefan, Gollub Randy L, Walton Esther, Hass Johanna, Smolka Michael N, White Tonya, Wassink Thomas H, Calhoun Vince D, Ehrlich Stefan
Abstract excerpt
Patients with schizophrenia show widespread cortical thickness reductions throughout the brain. Likewise, reduced expression of the γ-Aminobutyric acid (GABA) synthesizing enzyme glutamic acid decarboxylase (GAD1) and a single nucleotide polymorphism (SNP) rs3749034 in the corresponding gene have been associated with schizophrenia. We tested whether this SNP is associated with reduced cortical thickness, an...
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